Institute of Engineering and Technology is one of the leading institutions of North India with several departments covering all facets of Engineering and Technology. With a large number of distinguished faculty having national reputation and playing a leading role in adopting innovatives in teaching, the institute has come to be known for its high academic standards and value based education, imparted to students in both undergraduate and Post graduate courses.

Prof. A. K. Khare
Institute of Engineering and Technology,
Sitapur Road
Lucknow - 226 021
Phone: +91-522-2361692, 2361631
Fax: +91-522-2361631, 2731636

The Institute offers M.Tech as well as Ph. D. programmes in Biotechnology. Besides, teaching course Institute is also actively engaged in high quality research and development activities in the area of biotechnology, Bioinformatics & Nanobiotechnology. The MHRD, Govt of India under TEQIP scheme has recently given Centre of Excellence in Biotechnology. The Biotechnology research activities at Institute include site targeted drug designing, vaccine designing, gene therapy, secondary metabolites production using hairy root lines of medicinal plants & Bioreactor modeling simulation, control and optimization. Bioinfomatics facility helps Biotechnology Department to horn the skills of researcher in developing novel procedures and protocol in the area of computational molecular biology and databases / softwares development. Besides, Institute also provide general purpose information retrieval services to scientific community in the area of genomics, proteomics & Biotechnology. Such efforts are useful in developing strong networking with the institutions and industries. Institute is also rendering services to community & economy in the area of Biofertilizer, Sericulture and Aquaculture.

Equipments:

UV-VIS Spectrophotometer, Centrifuge, Microscope, Laminar Flow Chamber, Autoclave, Incubator, Oven, Fume Chamber, Electronic Balance, Shakers, Deep Freezer, Muffle furnace, BOD Incubator, Colorimeter, Rotary Water Bath, Water Purification System. Besides, a number of sophisticated equipments worth Rs. 75 Lacs are being procured under TEQIP / AICTE project, Govt. of India.

Databases / Tools:

The following databases / softwares tools have been developed by the Department of Biotechnology;

1. Online	TepiPred: A novel software tool to predict conserved and promiscuous HLA-DR binding sites. (www. ietlucknow.edu)
2. Offline	PMVD: A database on plant mosaic viruses CCPD: A database on promoters of cereal crops PlantProteaseDB: A database on plant derived proteases VTFBSS: A novel software to predict vertebrate encoding transcription factors PromSacnE: A software to extract promoters from eukaryotic systems

Type of Computer

1. Operating System	Window NT, LINUX
2. Number of Nodes	30
3. Existing Educational Softwares	MATLAB, Statistical Softwares, Biochemistry Lectures Modules, Biotechnology Lectures Modules

 

1. Public Awareness	Training programme in Bioinformatics
2. Educational / Human Resources Development	M.Tech & Ph.D. Programme in Biotechnology. (For admission in M. Tech. Biotechnology programme, advertisement is likely to appear in March / April, 2004.
3. Major Events held in Last Five Years	Research & Development Activities at IET, Lucknow, held in 2002. "Mantavya" Programme, a regular feature organized by students.
4. Events Planned for next Five Years	Two days Seminar / Workshop in Bioinformatics in March, 2004. Besides, the following R&D projects are underway: Computational Discovery of Regulatory Targets for Cancer Chemotherapy: The present work deals with the identification of regulatory targets at DNA/ Protein level and also to identify potential drug targets using machine learning approach for cancer chemotherapy. Analysis and development of in-silico tools for genome wide identification of vaccine candidates: The proposed research work deals with the analysis and development of in-silico tool for genome wide identification of vaccine candidates against human pathogens. In-Silico Genome comparisons and Cis-Element/ Transcription Factor Statistical Analysis: The proposed research work deals with the identification of transcription factors and their DNA binding sites/ cis-elements uning different statistical approaches at genome level under regulatory genomics part of biotechnology.

1. Mishra, B.N., Singh, S.P. and Kumar, A. (1997) A biofilm model for fixed bed anaerobic reactors: performance analysis considering diffusional resistances and axial dispersion. The Genetic Engineer & Biotechnologists., 17, 5-21.
2. Khan f, Agarwal S, Mishra BN (2003). Identification of GltC transcription factor binding DNA motifs and its novel co-regulated genes in nitrogen fixing bacteria. Online Journal of Bioinformatics, Volume 4, 7:106-114. (http://www.cpb.uokhsc.edu/ojvr/nitrofixbacteria2003abc.htm)
3. S Agrawal, BN Mishra, DS Yadav, G Chandra, R Goel, S Mishra, AK Khare, R Agrawal (2003). Recent trends in Drug Design: A Bioinformatics Approach. Proceedings of 5th International workshop on Computer Science and Information Tenchnologies, Ufa, Russia, Vol-1, September 16-18, 2003.
4. Ritu Srivastava, BN Mishra, DS Bhargava and Shipra Agarwal (2003). Edible oil extraction from sunflower seeds: A review. Journal Current Science 3(1): 53-62.
5. BN Mishra, S Agarwal and AK Khare (2001). Mathematical modelling of axial and recycle backmixing in a biofilm anaerobic fixed bad reactor. Different disorders: System: Indias: 2000 (Indias Publication, 2001: pp 320).
6. Mishra, B.N., Singh, S.P. and Kumar, A. (1998) Start-up and operational behaviour of an anaerobic fixed bed bioreactor treating pharmaceutical wastewater. Crop Research Journal, 16, 395-401.
7. Mishra, B.N. and Kumar, A. (1998) Operational characteristics of anaerobic fixed bed reactors: wastewater treatment and methane production. Journal of Nature Conservation, 10, 37-45.
8. Mishra, B.N. and Kumar, A. (1997) Anaerobic treatment of potato-starch wastewater using a foam bed bioreactor. The Genetic Engineer & Biotechnologists., 17, 165-173.
9. Kumar, A. and Mishra, B.N. (1997) 'Primer Premier' Biotechnology Software and Internet Journal, May/June, pp 31-33, review.
10. Mishra, B.N., Singh, S.P. and Kumar, A. (1997). A biofilm model for fixed bed anaerobic reactors: performance analysis considering diffusional resistances and axial dispersion. The Genetic Engineer & Biotechnologist., 17, 5-21.

Dr. B.N. Mishra
Assistant Professor & Head of Biotechnology &
Coordinator, Biotechnology Programme
Institute of Engineering and Technology,
Sitapur Road
Lucknow - 226 021 &
Convener, Research Degree Committee (RDC) Biotechnology,
U.P. Technical University, Lucknow

Phone : +91-522-2363200, 2733148 Ext. No. 206 (O)
              +91-522-2732527 (R)
Fax : +91-522-2361631
E-mail: profbmishra@yahoo.co.uk
            profbmishra@rediffmail.com
            biotechiet@rediffmail.com